Hormonal control of a gene encoding a putative PDR5-like ABC transporter in periwinkle
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Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter.
Pseudoxanthoma elasticum (PXE), the prototypic heritable connective tissue disorder affecting the elastic structures in the body, manifests with cutaneous, ophthalmologic, and cardiovascular findings, with considerable morbidity and mortality. The molecular basis of PXE has remained unknown, but the disease locus has recently been mapped to an approximately 500-kb interval on chromosome 16p13.1...
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ژورنال
عنوان ژورنال: Acta Botanica Gallica
سال: 2000
ISSN: 1253-8078,2166-3408
DOI: 10.1080/12538078.2000.10515842